Archive for Syndrome

Wild Blueberries May Mitigate Metabolic Syndrome Risk Factors

Portland, Maine (PRWEB) April 15, 2015

Two University of Maine studies reveal that a diet containing Wild Blueberries may positively impact certain characteristics of metabolic syndrome, including lipid status and inflammation. Having metabolic syndrome (MetS) dramatically increases one’s risk of developing type 2 diabetes and cardiovascular disease. MetS is defined as a cluster of concurrent risk factors: central obesity, insulin resistance, glucose intolerance, hypertension and dyslipidemia (an imbalance of fats in the blood).

“Metabolic syndrome is a growing health problem in the United States impacting roughly one-third of our adult population,” says Dorothy Klimis-Zacas, PhD, Professor of Clinical Nutrition at the University of Maine, and co-author of the two studies, published in the Journal of Nutritional Biochemistry and British Journal of Nutrition. “We are pleased to report our research indicates that Wild Blueberry consumption can have significant and positive health impacts on several components of this serious health condition.”

Kitty Broihier, MS, RD, LD, a nutrition advisor to the Wild Blueberry Association of North America, concurs, stating, “Studies like these help make the case that including Wild Blueberries in your daily diet may have a positive impact on some of the risk factors involved in metabolic syndrome.”

About the studies

The two studies were conducted on obese Zucker rats, which are a commonly used experimental model for studying metabolic syndrome in humans due to similarities in characteristics and disease progression. For both 8-week studies, the rats received a diet enriched with Wild Blueberries in an amount equivalent to 2 cups of berries per day for humans. The first study focused on examining markers of inflammatory status and their gene expression. Chronic inflammation is thought to be an underlying factor linking all the abnormalities of metabolic syndrome.

“Diet is one of the most manageable ways to impact inflammatory status, and our study documented for the first time that supplementing your diet Wild Blueberries for 8 weeks resulted in an overall reduction of the inflammatory status in the animals,” explains Klimis-Zacas. According to the researcher, this was achieved by reducing the circulating levels of two pro-inflammatory status markers and increasing the levels of anti-inflammatory markers, which resulted in positively impacting the gene expression of these markers as well.

The second study examined a Wild Blueberry-enriched diet’s impact on lipid metabolism and cholesterol levels. After eight weeks, there was a markedly beneficial impact on the obese Zucker rats’ lipid profiles: total blood cholesterol and triglyceride levels decreased, while beneficial HDL levels were maintained. The dietary treatment also favorably impacted the expression of key enzymes involved in lipid and cholesterol metabolism. “Wild Blueberries appear to function by decreasing fat synthesis, increasing fat oxidation, and aiding in reverse cholesterol transport, thus normalizing the abnormal lipid profile associated with metabolic syndrome,” summarized Klimis-Zacas.

Although these studies focused on the effects of whole-berry consumption, and not on the specific contributions of the bioactive components of Wild Blueberries, it is important to note, said Klimis-Zacas, that several previous studies suggest that the anthocyanin content of Wild Blueberries may be responsible for modifying risk factors for MetS.

For more information about the studies go to:

Journal of Nutritional Biochemistry (2013)

24:1508-12 – S. Vendrame, A. Daugherty, A.S. Kristo, P. Riso. D. Klimis-Zacas. Wild blueberry (Vaccinium angustifolium) consumption improves inflammatory status in the obese Zucker rat model of the metabolic syndrome.

British Journal of Nutrition (2014)

111:194-200 S. Vendrame, A. Daugherty, A.S. Kristo, D. Klimis-Zacas. Wild blueberry-enriched diet (Vacciniumangustifolium) improves dyslipidemia and modulates the expression of genes related to lipid metabolism in obese Zucker rats.

About the Wild Blueberry Association of North America

The Wild Blueberry Association of North America (WBANA) is a trade association of growers and processors of Wild Blueberries from Maine and Canada, dedicated to bringing the Wild Blueberry health story and unique Wild Advantages to consumers and the trade worldwide.

WBANA is dedicated to furthering research that explores the health potential of Wild Blueberries. Every year since 1997, WBANA has hosted the Health Research Summit in Bar Harbor, a worldwide gathering of scientists and researchers whose work is leading the way in learning more and more about the health benefits of Wild Blueberries.

More Diet Press Releases

Stamina Products Confirms AeroPilates Program Has Proven to Reduce Weight and Improve Health for Subjects with Metabolic Syndrome

Springfield, Mo. (PRWEB) November 19, 2014

Stamina Products, Inc. today announced that company representatives have verified their AeroPilates Reformers remain the only line of residential Pilates equipment complete with the patented Cardio Rebounder, which combines cardiovascular exercise and Pilates training into one uniquely effective fitness program. As indicated in a clinical study published in the Journal of Fitness Research, the combination of an AeroPilates program and dietary modification can result in marked improvement in health and significant weight loss for individuals with metabolic syndrome.

The purpose of the clinical research involving AeroPilates was to explore the benefits and effects of Pilates, low-impact cardiovascular exercise and nutritional intervention for individuals whose obesity has progressed to metabolic syndrome—the clinical name for the group of risk factors that can lead to Type II Diabetes and heart disease. Led by Denver Center for Health & Sport Science Medical Program Director Neil Wolkodoff, PhD, the six-week study involved ten intervention subjects and four control subjects, all of whom met the criteria for metabolic syndrome and were verified as “previously sedentary subjects” prior to the the study. As Wolkodoff stated after first publishing the results, the “patients made significant improvements in physiological measures and health status” after just six weeks of a balanced calorie-deficit diet and the combined strength and aerobics fitness elements AeroPilates offers.

Statistically Significant Results with AeroPilates

Published as “The Physiological and Health Effects of a Pilates Program combined with Nutritional Intervention on Subjects with Metabolic Syndrome,” the study indicates the AeroPilates Reformer helped lead to statistically significant (p<.05) benefits for intervention subjects:

Total weight decreased by 16.1 pounds
Body fat decreased by 2.58%
BMI decreased by 2.5
Waist and hip measurements decreased by 3.65 inches and 2.33 inches respectively
Systolic blood pressure decreased by 10 millimeters
Muscular endurance increased by 19.7%
Blood markers improved, including decreased total cholesterol, triglycerides, glucose levels, Homgebin A1 c, Plasmas Inhibitor Type 1 (PAI) and Leptin

Additional Compelling Indications from AeroPilates Study

The published Pilates Metabolic Syndrome Study results included several indications that AeroPilates is more efficient than similar forms of exercise. For example, the journal article stated that investigations with the intervention group “indicated that rebounding, or the trampoline-like jumping motion with the Pilates carriage was slightly better in energy expenditure per minute compared to elliptical, treadmill and recumbent cycling exercise at the same rate of perceived exertion.” Because that rate of energy output “is not found in other Pilates devices,” Wolkodoff theorized that it [the Cardio Rebounder] is “a factor in the physiological changes the subjects made in the short period of time.”

Wolkodoff also called attention to the importance of the results, given that the population being studied “has traditionally been resistant to weight loss.” Researchers appeared to be particularly encouraged because the amount of weight loss experienced “can reduce the risk of Type II Diabetes by 2/3.” With an estimated 30% of the U.S. population measuring as overweight or obese, embracing effective and comfortable exercise options is widely considered critical to fighting both Type II Diabetes and heart disease.

AeroPilates Co-Founder Marjolein Brugman, a renowned Pilates and fitness expert, notes that Wolkodoff’s findings reflect the evidence she has seen first hand during nearly ten years spent training clients with various AeroPilates Reformers: “Even clients who suffer through obesity and other debilitating issues can achieve noticeably better health and fitness through AeroPilates, because the complete, low-impact exercise program lets them burn calories, lose weight, get strong and become heart healthy—all while lying down, without hurting their joints.”

Brugman added that no matter how many times she sees it occur, “it is powerfully moving and inspirational to witness the transformation as people go from listless and often depressed to healthier, active and energetic.”

For more information on AeroPilates Reformers, the Cardio Rebounder or Wolkodoff’s research, contact Stamina Products at 417.889.7011 or by email at presscontact(at)


1. Wolkodoff, N.E., Andrick, R., Lazarus, E., Braunstein, B., and Patch, T. “The Physiological and Health Effects of a Pilates Program combined With Nutritional Intervention on Subjects with Metabolic Syndrome.” Journal of Fitness Research. 2013; 2: 17-29.